Frank Zappa Born in Baltimore, Maryland, on December 21, 1940, Frank Zappa was largely a self-taught musician, whose 30-year career embraced a wide variety of musical genres, encompassing rock, jazz, synth and symphonies. Avant-garde composers, as well as math and chemistry from his father's work, all fell into Zappa's mix of influences and comprised his unique approach to his art, coupled with a flouting of convention. Zappa also directed films, designed album covers and spoke about social issues. Although his unconventional aspect often overshadowed his brilliance, Zappa is highly respected as a musical pioneer. He died from prostate cancer on December 4, 1993, at age 52.